Bills vs Patriots Week 13 Odds, Picks & Predictions (Dec 6)

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Buffalo Bills at New England Patriots, Gillette Stadium Sunday, Dec 6, 2026 · 4:25 PM ET (late national window)

This is an AFC East game in Foxborough in December. Buffalo comes in off a Thanksgiving night game against the Chiefs, so it gets extra rest. New England comes in off a Sunday night game in Los Angeles.

Talking points - Rest vs travel: Buffalo has had about ten days off. The Patriots are coming back from a West Coast primetime trip. Who gets the better of that? - Weather: Early December in New England can mean wind and cold. Does that move you toward the under? - Division familiarity: Do division rematches favor the underdog in your experience, or is that a myth? - Stakes: Division games this late usually matter for seeding.

Lines will move before Sunday. Post the spread and total you're seeing.

What's your call on Bills-Patriots?

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