NFL Week 12 Picks & Discussion: Thanksgiving Week (Nov 25–30, 2026)

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Week 12 has games on five different days. It opens Wednesday, Nov 25 with Packers at Rams (8:00 PM ET, Netflix).

Thanksgiving, Thursday Nov 26 - Bears at Lions, 1:00 PM ET - Eagles at Cowboys, 4:30 PM ET (FOX) - Chiefs at Bills, 8:20 PM ET (NBC)

Black Friday, Nov 27 - Broncos at Steelers, 3:00 PM ET (Prime Video)

Sunday, Nov 29 highlights - Ravens at Texans, 1:00 PM ET - Seahawks at 49ers, 4:25 PM ET (FOX) - Patriots at Chargers, Sunday Night Football 8:20 PM ET (NBC)

Monday, Nov 30: Panthers at Buccaneers, 8:15 PM ET (ESPN).

There are no byes, so all 32 teams play.

Talking points - With a short week for the six Thanksgiving teams, how much do you weigh rest and travel? - Do you bet the holiday slate as a package or pick spots one game at a time? - Seahawks-49ers is a key NFC West game in the late window.

Lines will move fast around the holiday. Post the number you're seeing.

What are your Week 12 picks?

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